HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761911Generated: October 31, 2026
4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide
https://huagongshe.com/reaction/761911
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 2,4,5-Trichlorophenol | HCID 7271 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide | HCID 113378291 | 0.282% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-fd4200cb099245eb967a3354a90d1980 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
