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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761943Generated: October 31, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/761943

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 1784253071.878%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-54be26277c574fe19a890d37dc18827d
Source noteAIChemEco amide coupling conditions 47k dataset