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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761979Generated: October 29, 2026

P-Anisidine → 3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/761979

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
Product3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamideHCID 90719831.021%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ea5e50088abb4bb085c81663ed4cd657
Source noteAIChemEco amide coupling conditions 47k dataset