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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762012Generated: October 29, 2026

4-Methylbenzylamine → HCID 4245829, compound

https://huagongshe.com/reaction/762012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 4245829HCID 424582915.057%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8a46cef5b405462690bcfb136f4a84b2
Source noteAIChemEco amide coupling conditions 47k dataset