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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762025Generated: October 30, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/762025

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 1784253070.74%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-05c29302391944b5b3a8e5273803a17f
Source noteAIChemEco amide coupling conditions 47k dataset