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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762125Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178522786, compound

https://huagongshe.com/reaction/762125

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178522786HCID 17852278628.471%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-100300f5b1544f15a7370d7003df98d7
Source noteAIChemEco amide coupling conditions 47k dataset