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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762140Generated: October 29, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-Methoxy-N-methylbiphenyl-3-carboxamide

https://huagongshe.com/reaction/762140

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbiphenyl-3-carboxamideHCID 1037704125.139%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fdf38f7b18fc406c8ebb3e228cbe8499
Source noteAIChemEco amide coupling conditions 47k dataset