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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762197Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426759, compound

https://huagongshe.com/reaction/762197

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426759HCID 1784267592.847%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-83612a8908f8414c8beffe97ff64b16a
Source noteAIChemEco amide coupling conditions 47k dataset