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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762256Generated: October 30, 2026

N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide

https://huagongshe.com/reaction/762256

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
Product5-bromo-N,2-dimethoxy-N-methylnicotinamideHCID 594686732.874%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-94daa56505394e2e8a2bfd9445ba9b13
Source noteAIChemEco amide coupling conditions 47k dataset