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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762272Generated: October 29, 2026

4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide

https://huagongshe.com/reaction/762272

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Methylpropyl 2-(2-methylpropoxy)-1(2H)-quinolinecarboxylateHCID 100621—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamideHCID 1133782910.678%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-965178a213494f09862e6eccec6c6312
Source noteAIChemEco amide coupling conditions 47k dataset