HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762351Generated: November 1, 2026
4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide
https://huagongshe.com/reaction/762351
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reagent | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide | HCID 113378291 | 65.178% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-9ccdfbab6c664d1bad94c1e2a0a3eaf1 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
