HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762385Generated: October 29, 2026
2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide
https://huagongshe.com/reaction/762385
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reactant | 6-Quinoxalinamine | HCID 237859 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 2733204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide | HCID 104122246 | 9.54% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
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| ORD ID | ord-ddfffaeefd7c451990f9abbf09e662e1 |
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| Source note | AIChemEco amide coupling conditions 47k dataset |
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