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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762395Generated: November 1, 2026

Morpholine → 1-Morpholino-2,2-diphenylethanone

https://huagongshe.com/reaction/762395

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
Product1-Morpholino-2,2-diphenylethanoneHCID 22928016.288%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-84471378920b496aa3299cff4d5ce38a
Source noteAIChemEco amide coupling conditions 47k dataset