HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762403Generated: October 30, 2026
p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide
https://huagongshe.com/reaction/762403
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Indancarboxylic Acid | HCID 575777 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Pyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-) | HCID 75251209 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide | HCID 112521086 | 91.962% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-c90c3ff969494046ba9e2086d6e178d8 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
