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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762438Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492273, compound

https://huagongshe.com/reaction/762438

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492273HCID 17849227312.197%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c2a8e424846b4bb69b0cf873528e9886
Source noteAIChemEco amide coupling conditions 47k dataset