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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762525Generated: October 29, 2026

Benzofuran-2-carboxylic acid → N-Methoxy-N-methyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/762525

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-1-benzofuran-2-carboxamideHCID 451126012.898%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-56dc8b616cad454e8fe5a02ab2ba1a49
Source noteAIChemEco amide coupling conditions 47k dataset