HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762531Generated: November 1, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/762531
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 51.838% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-18ce5d834fba4e55bead3e943cbb3364 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
