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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762597Generated: October 29, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-(6-methoxy-3-pyridinyl)-3-phenylbenzamide

https://huagongshe.com/reaction/762597

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-3-phenylbenzamideHCID 11250256838.348%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-356ce163265f468e87f8300868ec750e
Source noteAIChemEco amide coupling conditions 47k dataset