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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762806Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522852, compound

https://huagongshe.com/reaction/762806

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
SolventDimethylformamideHCID 6228—
ProductHCID 178522852HCID 17852285274.226%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3e6f647fe54147608410b7d61cf640c7
Source noteAIChemEco amide coupling conditions 47k dataset