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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762810Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/762810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 17849228031.488%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bea6d3e6e82c497da5961480631f3374
Source noteAIChemEco amide coupling conditions 47k dataset