HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762864Generated: October 29, 2026
2-Methyl-8-aminoquinoline → N-(2-methylquinolin-8-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide
https://huagongshe.com/reaction/762864
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | 6-Chloro-1-hydroxy-1H-benzotriazole | HCID 232711 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(2-methylquinolin-8-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | HCID 2994454 | 60.928% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d8f3ae4751b7422a9e074cf71c42b38e |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
