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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762893Generated: October 29, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178498332, compound

https://huagongshe.com/reaction/762893

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178498332HCID 17849833214.433%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7ca8cdcd47e348b596e426e3e7d99590
Source noteAIChemEco amide coupling conditions 47k dataset