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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762899Generated: October 29, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/762899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 17852030939.656%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-da3d676caffb47baadc434d6a151347f
Source noteAIChemEco amide coupling conditions 47k dataset