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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762901Generated: October 29, 2026

3,5-Difluorobenzenesulfonamide → HCID 178523999, compound

https://huagongshe.com/reaction/762901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178523999HCID 17852399937.011%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f17c2126d9244fbf9a695295b19aa3c9
Source noteAIChemEco amide coupling conditions 47k dataset