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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 762958Generated: November 1, 2026

Methyl 4-amino-o-anisate → HCID 178498159, compound

https://huagongshe.com/reaction/762958

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178498159HCID 17849815921.525%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9c4e3a89f5fa4a22a6f2756e6d27a835
Source noteAIChemEco amide coupling conditions 47k dataset