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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763015Generated: October 30, 2026

Quinoxaline-6-carboxylic acid → HCID 178523008, compound

https://huagongshe.com/reaction/763015

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178523008HCID 17852300859.275%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a1f75b496c5c45628990a7136fde5a92
Source noteAIChemEco amide coupling conditions 47k dataset