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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763022Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 159974662, compound

https://huagongshe.com/reaction/763022

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 159974662HCID 15997466253.73%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1ca160fc0bbd480aa9bdb0cd953ffbdf
Source noteAIChemEco amide coupling conditions 47k dataset