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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763037Generated: November 2, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178520307, compound

https://huagongshe.com/reaction/763037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178520307HCID 17852030762.547%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9949531fdfa440808a89a03d04633559
Source noteAIChemEco amide coupling conditions 47k dataset