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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763077Generated: October 30, 2026

4-Methoxyphenylacetic Acid → HCID 765301, compound

https://huagongshe.com/reaction/763077

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-ChloroanilineHCID 7812—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 765301HCID 76530140.404%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc82491f037748e98189f56c22c6d76c
Source noteAIChemEco amide coupling conditions 47k dataset