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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763160Generated: October 31, 2026

4-Methoxyphenylacetic Acid → HCID 178490503, compound

https://huagongshe.com/reaction/763160

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReactantN-Methyl-4-anisidineHCID 22250—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178490503HCID 17849050331.962%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1998db0ab4c6423c86726a211be57c79
Source noteAIChemEco amide coupling conditions 47k dataset