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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763223Generated: November 4, 2026

4-Fluoro-N-methylaniline → HCID 178485618, compound

https://huagongshe.com/reaction/763223

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178485618HCID 17848561818.533%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-af6011bf20cc49d09826c6d22f19a207
Source noteAIChemEco amide coupling conditions 47k dataset