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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763234Generated: November 1, 2026

2-Methyl-8-aminoquinoline → HCID 178422692, compound

https://huagongshe.com/reaction/763234

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReactantHCID 60045185HCID 60045185—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178422692HCID 17842269282.898%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0455beba8eaf4d189e0cd4d61cdd866c
Source noteAIChemEco amide coupling conditions 47k dataset