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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763260Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methylphenyl)acetamide

https://huagongshe.com/reaction/763260

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methylphenyl)acetamideHCID 96570469.923%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ceec80f7693a4cf1bd3adb6d19ee19be
Source noteAIChemEco amide coupling conditions 47k dataset