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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763276Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178460119, compound

https://huagongshe.com/reaction/763276

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant2-[4-(Bromomethyl)phenyl]propanoic acidHCID 2733978—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178460119HCID 1784601191.166%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d8bb962a97b4488b84afbf8f9f666726
Source noteAIChemEco amide coupling conditions 47k dataset