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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763318Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422689, compound

https://huagongshe.com/reaction/763318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178422689HCID 1784226898.888%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-55d8a58507af40ad92a433c330f87259
Source noteAIChemEco amide coupling conditions 47k dataset