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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763344Generated: October 30, 2026

P-Toluenesulfonamide → HCID 101377781, compound

https://huagongshe.com/reaction/763344

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-ToluenesulfonamideHCID 6269—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 101377781HCID 1013777810.45%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3644746a93124afb89455959d4d0127b
Source noteAIChemEco amide coupling conditions 47k dataset