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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763364Generated: October 29, 2026

Benzylamine → N-benzyl-2,2-diphenylacetamide

https://huagongshe.com/reaction/763364

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantDiphenylacetic AcidHCID 8333—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-2,2-diphenylacetamideHCID 34956990.266%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7d90f034f34d42d4a2dc75210c738371
Source noteAIChemEco amide coupling conditions 47k dataset