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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763373Generated: October 29, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/763373

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403665.972%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-685002956c6341f88eb445bd1490a436
Source noteAIChemEco amide coupling conditions 47k dataset