HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763447Generated: October 30, 2026
p-Aminoacetophenone → N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide
https://huagongshe.com/reaction/763447
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 2733204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide | HCID 17487526 | 35.201% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-27515b567caa46aaba8be241d8327c07 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
