HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → 2-ethyl-4-(4-methoxyphenylcarbonyl)-8-(prop-1-enyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Oxazinone | HCID 21873527 | — |
| Product | 2-ethyl-4-(4-methoxyphenylcarbonyl)-8-(prop-1-enyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | HCID 89710545 | 62% |
Reaction Steps
Procedure & NMR Data: 137 mg (2.5 eq, 0.8 mmol) of p-Anisoyl chloride was added to a mixture of 49 mg (4 eq, 1.28 mmol) of NaH and 73 mg (0.32 mmol) of oxazinone P2 in THF (14 mL). 73 mg of P8 were obtained, yield 62%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835628B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-ef563e10b5ed471cbfbe7b39affab2bb |
| Source note | uspto-grants-2014_09 |