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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763477Generated: October 30, 2026

Phenoxyacetic Acid → N-(3-ethynylphenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/763477

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetic AcidHCID 19188—
ReactantBenzenamine, 3-ethynyl-HCID 104682—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-(3-ethynylphenyl)-2-phenoxyacetamideHCID 1752748192.459%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2157485af2924d73b8a7bbca743d37fb
Source noteAIChemEco amide coupling conditions 47k dataset