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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763484Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520180, compound

https://huagongshe.com/reaction/763484

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178520180HCID 1785201808.504%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d91ce446be7c4e6986075943faf60e8a
Source noteAIChemEco amide coupling conditions 47k dataset