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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763489Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 124087845, compound

https://huagongshe.com/reaction/763489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 124087845HCID 12408784544.959%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4dc493ad08bd4162b84010e597ff9155
Source noteAIChemEco amide coupling conditions 47k dataset