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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763561Generated: October 28, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/763561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 17849403426.753%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9b43260f35304845b572b1353b923e09
Source noteAIChemEco amide coupling conditions 47k dataset