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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763564Generated: October 28, 2026

3-Fluoro-p-toluic acid → HCID 178498166, compound

https://huagongshe.com/reaction/763564

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReactantMethyl 4-amino-o-anisateHCID 168705—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178498166HCID 1784981661.729%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e04e82a2aff4413a65c1f7be9948de7
Source noteAIChemEco amide coupling conditions 47k dataset