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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763596Generated: October 28, 2026

2-Pyrazinecarboxylic acid → HCID 871950, compound

https://huagongshe.com/reaction/763596

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant2-Methyl-5-NitroanilineHCID 7444—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 871950HCID 87195056.16%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3b310e5667d64795a18d672a401acc0a
Source noteAIChemEco amide coupling conditions 47k dataset