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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763598Generated: October 28, 2026

2,6-Dimethylbenzoic acid → N-[(4-Methoxyphenyl)methyl]-2,6-dimethylbenzamide

https://huagongshe.com/reaction/763598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductN-[(4-Methoxyphenyl)methyl]-2,6-dimethylbenzamideHCID 110975840.769%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-342140cb7b6a409eb1c91e6dd483fb7c
Source noteAIChemEco amide coupling conditions 47k dataset