反应详情

To 280 mg (0.90 mM) of 1-ethyl-3-{[(4-methylphenyl)thio]methyl}quinoxalin-2(1H)-one and 75.8 mg (0.90 mM) in a mixture of 6 ml of THF/water (50/50) were added portion wise 1.1 g (1.8 mM) of oxone. The reaction mixture was maintained under stirring for 30 min and water was added. A precipitate was filtrated and washed thoroughly with water, to give, after drying, 154 mg of 1-ethyl-3-{[(4-methylphenyl)sulfonyl]methyl}quinoxalin-2(1H)-one as a solid. Yield: 50%.

1. temperatureThe reaction mixture was maintained
2. filtrationA precipitate was filtrated
3. washwashed thoroughly with water
4. customto give
5. customafter drying