Sodium hydride → 11-(2-Iodobenzenesulfonyl)-11,12-dihydro-11,12-diazaindeno[2,1-a]fluorene

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

43 g (169 mmol) of 11,12-dihydroindolo[2,3-a]carbazole are initially introduced in 1000 ml of THF, and 8.9 g (223.3 mmol) of NaH (60% in oil) are added at 0° C. 24 g (80 mmol) of 2-iodobenzenesulfonyl chloride are subsequently added to the mixture, which is then stirred at 40° C. for 12 h. The organic phase is dried over MgSO4, and the solvent is removed in vacuo. The residue is recrystallised from acetone and finally sublimed in a high vacuum. Yield: 29 g (574 mmol), 72% of theory, purity according to HPLC 99.9%.

Herkunft & Nachweise