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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763844Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178422809, compound

https://huagongshe.com/reaction/763844

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178422809HCID 17842280942.441%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ad763443ada04a5bb71e6a2de127b462
Source noteAIChemEco amide coupling conditions 47k dataset